Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Peptide
KCNN3
Reactivité: Mammifères
Hôte: Synthetic
BP, WB, IHC
N° du produit ABIN939558
Aperçu rapide pour Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3) Peptide (ABIN939558)
Antigène
KCNN3
(Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
Origine
Mammifères
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Type de proteíne
- Synthetic
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Séquence
- ITELNDRSED LEKQIGSLES KLEHLTASFN SLPLLIADTL RQQQQQLLSA
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of KCNN3 antibody,
Alternative Names: KCNN3 control peptide, KCNN3 antibody Blocking Peptide, Anti-KCNN3 Blocking Peptide, Potassium Intermediate/Small Conductance Calcium-Activated Channel Subfamily N Member 3 Blocking Peptide, KCNN3, KCNN-3, KCNN 3, KCNN-3 Blocking Peptide, KCNN 3 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- KCNN3 (Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
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Sujet
- Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. KCNN3, a member of the KCNN family of potassium channel genes, encodes a protein that is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits.
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Poids moléculaire
- 81 kDa
Antigène
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